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I. Introduction

Classical Mechanics. Brian Cowan.

How body clocks rule our lives - BBC Tomorrow's World

Animals by the Numbers. Steve Jenkins. Mary Ann Asson-Batres. Endangered Species. Sean Sheehan. Brenda Peterson. Aquaculture Management. James W. Circadian Factors in Human Health and Performance. How to write a great review. The review must be at least 50 characters long. The title should be at least 4 characters long. Your display name should be at least 2 characters long.

Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences, and Countermeasures

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Remove FREE. Unavailable for purchase. Continue shopping Checkout Continue shopping. Chi ama i libri sceglie Kobo e inMondadori. View Synopsis. Choose Store. Or, get it for Kobo Super Points! Skip this list. Ratings and Book Reviews 0 0 star ratings 0 reviews. Overall rating No ratings yet 0. Short-term exhaustive memory and fine motor control. National aeronautics and space administration USA.

Phoenix mars lander. Astronaut centre of China. This article is published under license to BioMed Central Ltd. Table of Contents Abstract Circadian clock and sleep Disruption of circadian clocks affects physiology and performance Disturbances in circadian rhythms, sleep and performance in space Countermeasures and treatments Perspectives Declarations References. Review Open Access. Keeping the right time in space: importance of circadian clock and sleep for physiology and performance of astronauts.

Military Medical Research 1 Abstract The circadian clock and sleep are essential for human physiology and behavior; deregulation of circadian rhythms impairs health and performance. Space Circadian rhythm Sleep Performance Countermeasure. The circadian propensity for sleep increases during the sleep state, thus ensuring continued sleep despite the diminishing homeostatic need for it toward the end of the sleep cycle.

Anatomical and functional evidence indicates that there is a relationship between the SCN and the sleep-wake system. However, the major output is directed toward the adjacent subparaventricular zone and the dorsomedial nucleus of the hypothalamus. Cell-specific lesions in the ventral subparaventricular zone or the dorsomedial nucleus of the hypothalamus disrupt the circadian rhythms of sleep and wakefulness, suggesting that neurons in these areas must relay this influence [ 22 , 23 ].

Disruption of sleep-wake timing can lead to misalignment of rhythmicity in physiological variables. Sleep deprivation causes deterioration and a decrease in performance [ 24 ]. Insufficient or mistimed sleep can reduce the rhythmicity of clock-controlled genes [ 6 , 25 ].

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Figure 1 Network diagram of the circadian clock, sleep, physiology and behavior in space. Edited by: Donald K. Nat Rev Genet. Clin Sports Med. Annu Rev Neurosci. Cleve Clin J Med. Nat Rev Mol Cell Biol. Biol Proced Online. Cell Mol Life Sci. Brain Res. Exp Neurol. J Neurosci.

Curr Top Med Chem. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. J Comp Neurol.


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    Eur J Cell Biol. J Biol Rhythms. Physiol Behav. Signal Transduct. Life Sci Space Res. Environ Med. Neurosci Lett. Biomed Pharmacother. Psychosom Med. Int J Cogn Ergon. J Appl Physiol Biol Rhythm Res. Brain Res Brain Res Rev. Appl Ergon. Aviat Space Environ Med. Please review our Terms and Conditions of Use and check box below to share full-text version of article.

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